Molecular profiling of metastatic breast cancer and target-based therapeutic matching in an asian tertiary phase i oncology unit

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  • What: For the purposes of this analysis, the variants of uncertain significance were excluded. The authors report a retrospective analysis of MBC patients enrolled in the Integrated Molecular Analysis of Cancer (IMAC) study from April 28, 2014, to January 31, 2022. In this retrospective study of a cohort of MBC patients from a tertiary oncology centre in Asia, the authors report a higher PFS for patients receiving matched versus unmatched treatment, a finding consistent with prior publications . The authors report a subgroup of patients who received ICI treatment for MBC (19/105 patients) of whom five had . . .

     

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