Molecular recognition of a membrane-anchored hiv-1 pan-neutralizing epitope

HIGHLIGHTS

  • who: Johana Torralba from the University of the Basque Country (UPV/EHU), , Bilbao, Spain have published the paper: Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope, in the Journal: (JOURNAL)
  • what: Using a combination of structural and biophysical techniques the authors assess the role of conserved TMD helix residues in the C-MPER recognition process that evolves in a membrane environment. The authors measured the breakthrough forces of the different SPBs to quantitatively determine the nanomechanical resistance to membrane rupture. The authors surmise that the adoption of a quaternary structure does not . . .

     

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