HIGHLIGHTS
- who: The Lysine Specific Demethylase- and collaborators from the CNRS UMR , Laboratory of Tissue Biology and Therapeutic Engineering, Université, PRABI-AMSB, Université, University have published the research: Molecular Sciences, in the Journal: (JOURNAL)
- what: The authors show that LSD1 interacts with transcription factor SOX9 and is recruited to promoter of COL9A1. Interestingly the authors observe that OA cartilage displays stronger LSD1 immunostaining compared with normal and the authors demonstrate that depletion of LSD1 in OA prevents decrease in COL9A1 following Il-1β treatment. The authors focused on the role of the Lysine-Specific Demethylase 1 . . .
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