HIGHLIGHTS
- who: Anti-GAD Antibodies and collaborators from the Neuroncology Unit, IRCCS Mondino Foundation, Pavia, Italy have published the research: Molecular Sciences, in the Journal: (JOURNAL)
- future: Studies analyzing larger cohorts are needed to clarify whether the different neurological syndromes are associated with particular HLA alleles.
SUMMARY
Glutamic acid decarboxylase (GAD) is an intracellular enzyme fairly expressed in neurons and insulin-secreting pancreatic β cells, whose physiologic function is the decarboxylation of glutamate to gamma-aminobutyric acid (GABA). This diversity of clinical 3 of 22 reflects, at least in part, different epitope specificity . . .
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