HIGHLIGHTS
- who: Fibrogenesis and collaborators from the Department of Biomedical Sciences, College of Medical Convergence, Catholic Kwandong University have published the research: Molecular Sciences Molecule That Promotes Cellular, in the Journal: (JOURNAL) of 24/05/2022
- what: The authors show that ONG41008 potently induces cellular senescence in pathogenic myofibroblasts and oncogene-induced senescence (OIS)/cancer cell senolysis in several cancer cell lines being representative of aggressive forms of human cancer, resulting in cellular escape from fibrogenesis and tumorigenesis. The authors also discovered that unique transcriptomes are responsible for driving RS; RNA-seq analysis was conducted to . . .
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