HIGHLIGHTS
- who: Ewan Douglas, Fowler and Spyros, Zissimopoulos from the School of Biosciences, College of Biomedical and Life Sciences, Cardiff University, Cardiff , AX, UK have published the research work: Molecular Subcellular and Arrhythmogenic Mechanisms in Genetic RyR2 Disease, in the Journal: Biomolecules 2022, 12, 1030. of /2022/
- what: In the following, the authors aim to describe determinants of RyR2 regulation as interacting layers consisting of: the pore-forming domains, domains that directly interact with the pore, domains that indirectly regulate the pore through intermediaries, or interacting regulatory proteins. The authors focus on three RyR2-associated proteins . . .
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