Molecular targeting of epidermal growth factor receptor (egfr) and vascular endothelial growth factor receptor (vegfr)

HIGHLIGHTS

  • who: Nichole E. M. Kaufman and colleagues from the Department of Chemistry, Louisiana State University, Baton Rouge, LA, USA have published the research: Molecular Targeting of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Receptor (VEGFR), in the Journal: Molecules 2021, 26, 1076. of /2021/
  • what: Most of the models proposed are based on crystal or NMR structures of individual domains as an elucidation of the entire intact protein receptor is not feasible.

SUMMARY

    Each ErbB family member protein consists of a large glycosylated N-terminal extracellular domain (ECD . . .

     

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