HIGHLIGHTS
- who: Jielu Liu from the Karolinska Institute Uppsala University have published the paper: Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models, in the Journal: Scientific Reports Scientific Reports
- what: This study demonstrated that exposure to monensin in guinea pig trachea reduced MC staining intensity and MC numbers by causing cell death.
- how: The study highlights that an expansion of MC populations is fundamental for the development of AHR and airway inflammation in the used models which are highly relevant for reactions seen in allergic asthma.
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