Monocarboxylate transporter upregulation in induced regulatory t cells promotes resistance to anti-pd-1 therapy in hepatocellular carcinoma patients

HIGHLIGHTS

• who: Jinren Zhou and colleagues from the Xiangya Hospital, Central South University, China have published the research work: Monocarboxylate transporter upregulation in induced regulatory T cells promotes resistance to anti-PD-1 therapy in hepatocellular carcinoma patients, in the Journal: (JOURNAL)
• what: The authors propose that by evaluating MCT expression and suppressing the MCT signaling, the efficacy of therapeutic strategies can be improved. The authors assessed the underlying mechanisms of resistance to anti-PD-1 therapy according to the generation, activation, and function of iTregs. The study provides insights into the modulation of immunosuppression in . . .
  

   

  

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