HIGHLIGHTS
- who: Christiane Desel from the University of Veterinary Medicine Hannover, Germany have published the article: Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant, in the Journal: (JOURNAL)
- what: The study provides evidence that Th17 immunity induced by a Mincle-targeting adjuvant depends on the recruitment of CCR2+ inflammatory monocytes.
- future: The results show a dichotomy in the functional roles of monocytes and neutrophils with implications for future adjuvant optimization and investigations of cellular and molecular mechanisms. Candidates to be tested in future experiments include IL . . .
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