More than a marker: potential pathogenic functions of map2

HIGHLIGHTS

  • who: Robert A. Sweet from the University of Wisconsin-Madison, United States have published the article: More than a marker: potential pathogenic functions of MAP2, in the Journal: (JOURNAL)
  • what: The aim of this review is to summarize the current understanding of MAP2 function and regulation and review the existing evidence for MAP2 dysregulation in disorder, discussing potential forms and consequences of MAP2 pathology.

SUMMARY

    MAP2 creates local dendritic reservoirs of proteins critical to LTP/LTD, including PKA, EB3, RNA particles and polyribosomes (Lim and Halpain, 2000; Nielsen et_al, 2002; Ostroff . . .

     

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