HIGHLIGHTS
SUMMARY
The most advanced therapies in regenerative medicine use gene editing, stem_cells, and tissues to handle a wide range of conditions. One of their purposes is to stimulate the endogenous repair of tissues by manipulating stem_cells or optimizing the intrinsic characteristics and plasticity of differentiated cells in adult tissues. Thanks to their easy access by means of minimally invasive procedures without generating aesthetic problems, their easy and rapid in_vitro expansion, and their great ability to respond to extrinsic factors, oral fibroblasts represent an attractive and interesting resource for regenerative medicine. Although there is already evidence . . .
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