Motif models proposing independent and interdependent impacts of nucleotides are related to high and low affinity transcription factor binding sites in arabidopsis

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  • who: Victor G. Levitsky from the Max Planck Institute of Molecular Physiology, Germany (RIBES), Radboud University, Nijmegen, Netherlands, Department of Natural Science have published the paper: Motif models proposing independent and interdependent impacts of nucleotides are related to high and low affinity transcription factor binding sites in Arabidopsis, in the Journal: (JOURNAL)
  • what: The analysis proposes that while the standard PWMs describe the position-specific conserved nucleotide context that is associated with sites of relatively higher affinity, the alternative models BaMM/SiteGA incorporate many dependencies of the various positions, which allows these models to achieve . . .

     

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