HIGHLIGHTS
- who: Rodrigo O. de Castro from the (UNIVERSITY) have published the article: Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development, in the Journal: (JOURNAL)
- what: The authors report that testis-specific specific deletion of chd4 is essential for testis development and sustained germ cell production, while chd3 deletion results in no apparent phenotype. The authors propose these results suggest a possible mechanism by which Chd4 contributes to early germ cell development regulating genes that are required for survival/maintenance of spermatogonia cells. Genome wide Chd4 chromatin binding To further investigate . . .
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