Mouse mesoderm-specific transcript inhibits adipogenic differentiation and induces trans-differentiation into hepatocyte-like cells in 3t3-l1 preadiocytes

HIGHLIGHTS

  • who: Yoshito Kadota from the (UNIVERSITY) have published the research work: Mouse mesoderm-specific transcript inhibits adipogenic differentiation and induces trans-differentiation into hepatocyte-like cells in 3T3-L1 preadiocytes, in the Journal: (JOURNAL)
  • what: This study evaluated the effects of Mest in 3T3-L1 cells on adipogenic differentiation using Oil Red O staining and on hepatocyte trans-differentiation using RT-PCR and morphology observation.

SUMMARY

    The Mest mRNA levels are markedly upregulated in white adipose_tissue in obese mice, and its increased expression correlates with the size of adipocytes. In transgenic . . .

     

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