Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis

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  • who: R. E. H. Karsten from the Pharmaceutical Analysis Research Group, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan, AV Groningen, The Netherlands have published the article: Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis, in the Journal: (JOURNAL)
  • what: The authors demonstrate that mPCLS can be used to study human DIC onset and progression in 48 h period. The authors aim to achieve a humanlike mouse PCLS model to study DIC, by changing the BA pool in mouse PCLS through addition of a human-like . . .

     

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