Mpp6 stimulates both rrp6 and dis3 to degrade a specified subset of mtr4-sensitive substrates in the human nucleus

HIGHLIGHTS

  • who: MTR and colleagues from the Graduate School of Biostudies, Kyoto University, Kyoto, Kyoto, Japan, Division of Gene Expression have published the research: MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus, in the Journal: (JOURNAL)
  • what: The authors demonstrate a facilitative function of that composes a specific part of MTR4dependent decay by the human Using RNA polymerase II-transcribed poly(A)+ accumulation as an indicator of a perturbed the authors found functional redundancy between and in the decay of these poly(A)+ transcripts. binding . . .

     

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