Mrna vaccines and hybrid immunity use different b cell germlines against omicron ba.4 and ba.5

HIGHLIGHTS

  • who: Emanuele Andreano from the (UNIVERSITY) have published the research: mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5, in the Journal: (JOURNAL) of 16/03/2023
  • what: The authors evaluated the neutralizing activity against BA.4 and BA.5 variants of 482 neutralizing human monoclonal_antibodies (nAbs) that neutralized the original Wuhan virus. The remaining germlines showed a 1.67- to 45.43-fold reduction in their GM-IC100 against the Omicron variants tested in this study compared to the Wuhan virus. The authors interrogated exclusively the . . .

     

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