Mrs3p, mrs4p, and frataxin provide iron for fe-s cluster synthesis in mitochondria*

HIGHLIGHTS

  • who: Yan Zhang from the (UNIVERSITY) have published the research: Mrs3p, Mrs4p, and Frataxin Provide Iron for Fe-S Cluster Synthesis in Mitochondria*, in the Journal: (JOURNAL) of August/11,/2006
  • what: In the experiment , holoprotein formation was equivalent for wild_type and ⌬mrs3/4; similarly, holoprotein formation was equivalent for ⌬yfh1 and ⌬⌬⌬. In view of the studies , it appears that frataxin does indeed play a direct role in Fe-S formation and in mobilization of endogenous iron stores within mitochondria for Fe-S cluster synthesis.

SUMMARY

    The overall structure of frataxin . . .

     

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