Mrtf-a-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via mir-1273g-3p/mtor axis in alzheimer models

HIGHLIGHTS

  • who: Wei Zhang and collaborators from the Affiliated Wuhan Resources and Wisco General Hospital, Wuhan University of Science and Technology, Wuhan, Hubei, China have published the paper: MRTF-A-mediated protection against amyloid-u03b2-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models, in the Journal: (JOURNAL)
  • what: This study shows that the expression of MRTF-A in the hippocampus of Tg2576 transgenic mice is reduced and the overexpression of MRTF-A mediated by lentiviral vectors carrying MRTF-A significantly reduces the accumulation of hippocampal u03b2-amyloid peptide . . .

     

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