Mrtf may be the missing link in a multiscale mechanobiology approach toward macrophage dysfunction in space

HIGHLIGHTS

  • who: MRTF and colleagues from the Leipzig University, Germany have published the research work: MRTF may be the missing link in a multiscale mechanobiology approach toward macrophage dysfunction in space, in the Journal: (JOURNAL)
  • what: The authors aim to introduce MRTF in the context of spaceflight by taking a multiscale approach to past research on Mu03d5 dysregulation and other diseases. The authors propose mechanisms for the most well-studied Mu03d5 phenotype changes in space: pro/anti-inflammatory activation, morphology, migration, and phagocytosis. In Table 3, the authors compare Mu03d5 to non-differentiated monocytes, a cell . . .

     

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