HIGHLIGHTS
- who: Qi Zhang et al. from the Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China have published the article: MTHFR Polymorphism and Folic Acid Supplementation Influence Serum Homocysteine Levels in Psoriatic Patients Treated with Methotrexate, in the Journal: (JOURNAL)
- what: The authors found that patients with the TT genotype showed significantly higher serum homocysteine levels before starting MTX therapy than patients with the wild-type (CC) or CT genotype. This study shows that the level of serum homocysteine might not only positively correlate psoriasis severity but also with the curative effect of MTX.
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