Mtor inhibition as a novel gene therapeutic strategy for diabetic retinopathy

HIGHLIGHTS

  • who: Steven Hyun Seung Lee and colleagues from the CdmoGen Co, Ltd, Cheongju, Department of Ophthalmology, Asan Medical Center, University have published the research work: mTOR inhibition as a novel gene therapeutic strategy for diabetic retinopathy, in the Journal: PLOS ONE of May/31,/2022
  • what: Having previously demonstrated the potential of a mTOR-inhibiting shRNA packaged in a recombinant adenoassociated virus to address a variety of angiogenic retinal diseases here the authors explore the effects of rAAV2-shmTOR-SD in a streptozotocin-induced diabetic mouse model.
  • how: Next the authors examined in . . .

     

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