HIGHLIGHTS
- who: Masaki Michishita and colleagues from the Chiba Cancer Center, Japan have published the Article: mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma, in the Journal: (JOURNAL)
- what: In the present study, HH signaling, such as AY9944, cyclopamine, and jervine, is identified as a candidate to suppress the self-renewal ability of CSCs from the CTBp line, although detailed analysis has not been performed.
SUMMARY
Molecular-targeted drugs were developed to directly act on molecular cancer cell abnormalities and selectively target various signaling pathways . . .
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