HIGHLIGHTS
- who: Antonio Ferreri and collaborators from the Department of Dermatology, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany have published the research: mTORC1 Activity in Psoriatic Lesions Is Mediated by Aberrant Regulation through the Tuberous Sclerosis Complex, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
- what: As the authors could previously show that AKT is hyper-activated in psoriatic skin, the authors focused on residues in TSC2, which are mainly regulated by AKT. The authors propose that the psoriatic inflammation drives TSC2 phosphorylation, resulting in its spatial re-distribution, which . . .
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