HIGHLIGHTS
- who: Raymond Noordam from the ParticipantsAnalyses were performed locally by the different participating studies. Discovery and replication analyses comprised men and women between the age of , and , years, and were conducted separately for the different contributing (self-defined) ancestry groups, including: European, African, Asian, Hispanic and Brazilian (discovery analysis only). Descriptions of the different participating studies are described in detail in the Supplementary Notes , and, and studyspecific characteristics (sizes, trait distribution and data preparation) are presented in Supplementary Tables, . Every effort was made to include as many studies as possible. Ethical regulations. The present work was approved . . .
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