HIGHLIGHTS
- who: ClpP activators and collaborators from the University of Arkansas for Medical Sciences, United States have published the article: Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer, in the Journal: (JOURNAL)
- what: The aim of this study was to complete a multi-omics profile of TNBC cells following pharmacological ClpP activation. Analysis, the top 50 significantly altered endogenous metabolic networks (EMNs) were identified by MetaCore software, with 42 of these 50 EMNs occurring in both ONC201 and TR-57 treated WT SUM159 cells . This study has identified significant . . .
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