Multi-omics analysis reveals rna splicing alterations and their biological and clinical implications in lung adenocarcinoma

HIGHLIGHTS

  • who: Quanyou Wu from the (UNIVERSITY) have published the research work: Multi-omics analysis reveals RNA splicing alterations and their biological and clinical implications in lung adenocarcinoma, in the Journal: (JOURNAL) of 27/01/2022
  • what: The authors integrated multi-omics data to comprehensively and robustly investigate the landscape of splicing alterations in LUAD based on a total of 799 LUAD samples and 204 adjacent-normal samples. In this study, seven different types of ASEs were identified, including retained intron (RI), mutually exclusive exons (ME), exon skip (ES), alternate terminator (AT), alternate promoter (AP), alternate . . .

     

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