Multi-omics hecatos dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

HIGHLIGHTS

  • who: Marcha Verheijen from the DepartmentMaastricht University have published the paper: Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds, in the Journal: (JOURNAL) of 11/07/2022
  • what: Rather than comparing single time point experiments with the corresponding controls this analysis focused on differences in the time-course profiles; 3) Normalized expressed genes or detected proteins of each time point of a treatment/dose group was compared with the time point 0 hr (T0).
  • how: The models were designed to resemble the repetitive administration (1x daily) of either a . . .

     

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