Multi-strategy assessment of different uses of qsar under reach analysis of alternatives to advance information transparency

HIGHLIGHTS

SUMMARY

    For instance, applicants may embed valuable information regarding their QSAR predictions within their AoA despite missing (Q)SAR Prediction Reporting Format (QPRF) documentation. In response to the data gap, this study explores three novel uses of QSAR information in REACH authorization: QSAR data, which falls under QPRF, QSAR usage in weight of evidence (WoE), and_(3) QSAR battery test integrated systems (ITS). The Need for Heightened Transparency in REACH AoA QSAR Data Detailed and open QSAR information is important for regulatory decision making, especially within the context of authorization, where alternatives may lack experimental . . .

     

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