Multifaceted roles of sarm1 in axon degeneration and signaling

HIGHLIGHTS

  • who: Catherine A. Collins from the University of Illinois at Chicago, United States have published the paper: Multifaceted roles of SARM1 in axon degeneration and signaling, in the Journal: (JOURNAL)
  • what: The SARM1 NADase enzyme is an attractive druggable target for intervening neuropathies and a variety of neurodegenerative diseases.
  • future: Future study of the cellular mechanism of its interactions with SARM1 may provide important insights into SARM1's functions in signaling as well as degeneration. the inhibition of degeneration in both axons and dendrites (Xiong and Collins 2012 Hao et_al 2019) which contrasts . . .

     

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