Multimodal regulation of the osteoclastogenesis process by secreted group iia

HIGHLIGHTS

• who: (sPLA and collaborators from the Instituto de Biología y Genética Molecular (CSIC), Spain Western Sydney University, Penrith have published the research work: Multimodal regulation of the osteoclastogenesis process by secreted group IIA, in the Journal: (JOURNAL)
• what: The authors provide evidence of a multimodal regulation of the osteoclastogenesis and of mature osteoclast activity by sPLA2IIA, using RAW264.7 murine macrophages as osteoclast precursors, or primary precursor cells from bone marrow of wild-type (wt) and Pla2g2a-knockout (ko) BALB/cJ mice. Within these model systems, the transcriptional remodeling induced by RANKL results . . .
  

   

  

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