Multimodal treatment with curative intent in a germline

HIGHLIGHTS

• who: Gianluca Mauri from the (UNIVERSITY) have published the Article: Multimodal treatment with curative intent in a germline, in the Journal: (JOURNAL)
• what: The authors report a clinical case of a platinum-sensitive metastatic AC patient in which the identification of a BRCA2 germline mutation drove a personalized multimodal approach with potential curative-intent.

SUMMARY

TP53 mutations (41-53%) and KRAS mutations (40%) are among the most common alterations found in ACs, while ERBB2/3 alterations and microsatellite instability (MSI) are rarer but may represent potential therapeutic targets in the metastatic . . .

 



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