HIGHLIGHTS
- who: Lise Mangiante from the (UNIVERSITY) have published the research: Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity, in the Journal: (JOURNAL) of 25/Dec/2021
- what: Through a large series of whole-genome sequencing data, integrated with transcriptomic and epigenomic data using multiomics factor analysis, the authors demonstrate that the current World Health Organization classification only accounts for up to 10% of interpatient molecular differences. The authors show that these four dimensions are complementary, capture major interpatient molecular differences and are delimited by extreme phenotypes that . . .
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