Multiplatform molecular analysis of vestibular schwannoma reveals two robust subgroups with distinct microenvironment

HIGHLIGHTS

  • who: Alexander P. Landry from the Division of Neurosurgery, University of Toronto, Toronto, ON, Canada have published the Article: Multiplatform molecular analysis of vestibular schwannoma reveals two robust subgroups with distinct microenvironment, in the Journal: (JOURNAL)
  • what: The authors explore the transcriptome and methylome of vestibular schwannomas.
  • future: The limited number of patients with SH3PDX2A-HTRA1 fusion in this cohort precluded an analysis of this important mutation and further work with larger cohorts will be required to determine its relevance in the context of these newly described subgroups.

SUMMARY

     

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