Multiple and additive functions of aldh3a1 and aldh1a1

HIGHLIGHTS

• who: Natalie Lassen from the Animals-Transgenic Aldh1a1(⫺/⫺), Aldh3a1(⫺/⫺), and Aldh1a1(⫺/⫺)/Aldh3a1(⫺/⫺) mice and their wild type counterparts (C BL/ JX129/sv) were bredGeneration of Aldh1a1(⫺/⫺) and Aldh3a1(⫺/⫺) single knock-out animals has been previously described (26, ). Aldh1a1(⫺/⫺)/ Aldh3a1(⫺/⫺) double knock-out mice were generated by breeding , homozygous hybrids of Aldh1a1(⫺/⫺) and Aldh3a1(⫺/⫺) mice. C BL/ JX129/sv mice are , hybrids of control C BL/ J and, sv mice, the genetic background of all knock-out lines used in this study. Animals were maintained in a temperature-controlled room (21, °C) on a, h light/ dark cycle . . .
  

   

  

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