HIGHLIGHTS
- who: . and colleagues from the Shinshu University, Japan have published the article: Multiple aspects of lymphatic dysfunction in an mouse model of hypercholesterolemia, in the Journal: (JOURNAL)
- what: The authors directly investigated various aspects of lymphatic collecting vessel function in ApoE-deficient mice on a HFD. As explained in previous publications, the authors propose that an upward shift in the u0394P for closure vs. D/Dmax relationship reflects an increase in valve leaflet stiffness. Through comprehensive analyses of collecting lymphatic function using vessels from hypercholesterolemic ApoE-/- mice, the authors demonstrate here that hypercholesterolemia significantly compromises . . .
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