HIGHLIGHTS
SUMMARY
The homeostatic maintenance of most organs and tissues is ensured throughout the life of an organism by a controlled balance of cell division and cell death. Today, studies of neuronal cell death are mainly performed in_vitro using mammalian cell lines because of animal anatomical complexity. Reliable and simple animal models are very useful to in_vivo studies on neuronal cell death and its role in the organism as a whole. Since the classification of death into three main categories-apoptosis, necrosis, and autophagy-50 years ago, cell death into three main categories-apoptosis, necrosis, and . . .
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