Multiple phosphorylations of sr protein srsf3 and its binding to m6a reader ythdc1 in human cells

HIGHLIGHTS

  • who: Takanori Tatsuno and Yasuhito Ishigaki from the (UNIVERSITY) have published the research: Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m6A Reader YTHDC1 in Human Cells, in the Journal: Cells 2022, 1461 of /2022/
  • what: The authors demonstrate the position of SRSF3 phosphorylation sites and detail the amino_acid sequences needed for the binding between SRSF3 and YTHDC1. Previous reports revealed that the RS domain of SRSF3 appeared sufficient for binding during splicing or nuclear export , whereas this study showed that the RRM region of SRSF3 could bind to YTHDC1 and thereby support . . .

     

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