HIGHLIGHTS
- who: Nelson Ferreira from the (UNIVERSITY) have published the paper: Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential, in the Journal: (JOURNAL)
- what: Using an array of biophysical biochemical cellular and in vivo analyses the authors demonstrate that compared to α-Syn alone substoichiometric concentration of p25α redirects α-Syn into unique α-Syn/p25α strain with different structure and enhanced in vivo prodegenerative properties. The authors generated a novel α-Syn strain by incubating α-Syn in the presence of p25α, and compared this α-Syn/p25α PFF to a control . . .
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