Multipotent basal stem cells, maintained in localized proximal niches, support directed long-ranging epithelial flows in human prostates

HIGHLIGHTS

• who: Mohammad Moad from the InstitutNewcastle University, Newcastle upon Tyne , AD, UK have published the paper: Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates, in the Journal: (JOURNAL) of August/15,/2017
• what: By combining quantitative clonal mapping with 3D reconstruction of adult human prostates the authors show basal stem cells confined to discrete niches juxta-urethral ducts generate bipotent basal progenitors epithelial migration streams.
• future: Work is required to identify a marker for luminal stem_cells in situ to better characterize their functional . . .
  

   

  

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