Multiscale computer modeling of spreading depolarization in brain slices

HIGHLIGHTS

  • who: Significance Statement and colleagues from the Program in Biomedical Engineering, SUNY Downstate Health Sciences University and NYU Tandon School of have published the research: Multiscale Computer Modeling of Spreading Depolarization in Brain Slices, in the Journal: (JOURNAL)
  • what: The model showed that SD speed was augmented by propionate and hypoxia and suggested that changing the ECS was the principle mechanism through which they influence SD. The model is not specific to any particular brain area, as the authors aimed to reproduce general properties applicable to different brain regions and to different pathophysiologies. The authors . . .

     

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