Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies

HIGHLIGHTS

• who: Matthias Edinger and collaborators from the DepartmentUniversity Erlangen, Frankfurt am Main, Germany have published the research work: Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies, in the Journal: (JOURNAL) of March/16,/2021
• what: The authors demonstrate that MCMV reactivation and dissemination was modulated by MCMV-specific antibodies thus demonstrating in vivo protective activity of antiviral antibodies. In the model , the authors have shown that the GVHD-induced loss of lymphoid tissue and function contributes to MCMV reactivation, even in the absence of pharmacologic immunosuppression. In this report . . .
  

   

  

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