Murine infection with bioluminescent leishmania infantum axenic amastigotes applied to drug discovery

HIGHLIGHTS

  • who: David Mendes Costa from the Universidade have published the paper: Murine infection with bioluminescent Leishmania infantum axenic amastigotes applied to drug discovery, in the Journal: Scientific Reports Scientific Reports
  • what: The authors investigated the infectivity of luciferase-expressing L infantum axenic amastigotes in BALB/c mice. The authors propose the use of this rapid bioluminescence-based model for a time and cost effective preliminary in_vivo testing of promising compounds against L infantum.

SUMMARY

    The authors found that this parasite form is highly infectious and generates a robust bioluminescent signal in . . .

     

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