HIGHLIGHTS
- who: Martina Pauk from the Institute of Musculoskeletal Medicine, University Hospital, LMU Munich, Munich, Germany have published the research: Muscle and Bone Defects in Metastatic Disease, in the Journal: (JOURNAL)
- what: The present review addresses most recently identified mechanisms implicated in metastasis-induced bone resorption and muscle-wasting syndrome known as cachexia. The authors presented an overview of recent discoveries related to metastatic bone and muscle disease.
- future: Inhibition of the BMP pathway by LDN193189 was shown to enhance bone metastasis development in breast cancer suggesting future studies are needed to elucidate the . . .
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