HIGHLIGHTS
- who: Sebastian Schmeisser from the McGill University Canada have published the article: Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling, in the Journal: (JOURNAL) of December/24,/2019
- what: Using tissue-specific RNAi and transgenic approaches, the authors show here that the activation of PKA exclusively within the muscle can increase the lifespan in a non-cell-autonomous manner, likely through a lipid signaling pathway that is transduced through peripheral tissues. By doing this, the authors aimed to identify features that were significantly more abundant under mrkin-2 RNAi while being unchanged or . . .
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