Muscle-specific splicing factors asd-2 and sup-12 cooperatively switch alternative pre-mrna processing patterns of the adf/cofilin gene in caenorhabditis elegans

HIGHLIGHTS

  • who: Genta Ohno and colleagues from the Laboratory of Gene Expression, Graduate School of Biomedical Science, Tokyo Medical and Dental University, Tokyo, Japan, Department of Functional Genomics have published the Article: Muscle-Specific Splicing Factors ASD-2 and SUP-12 Cooperatively Switch Alternative Pre-mRNA Processing Patterns of the ADF/Cofilin Gene in Caenorhabditis elegans, in the Journal: (JOURNAL) of October/11,/2012
  • what: By disrupting juxtaposed CUAAC repeats and UGUGUG stretch in intron 1A the authors demonstrate that these elements are required for retaining intron 1A as well as for switching the processing patterns . . .

     

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