Mutant and non-mutant neoantigen-based cancer vaccines: recent advances and future promises

HIGHLIGHTS

  • who: Cancer immunotherapy and collaborators from the Universitu00e9 Paris-Saclay, Villejuif, France have published the article: Mutant and non-mutant neoantigen-based cancer vaccines: recent advances and future promises, in the Journal: (JOURNAL)
  • what: The present review discusses tumor-associated antigens (TAAs) and neoantigens and their use as targets in peptide- and RNA-based therapeutic vaccines.
  • future: These mutant neoantigens have opened up new perspectives in active immunotherapy to a wide range of cancer types without the need for isolating tumor-reactive CTL clones and establishing autologous cancer cell lines . The design of . . .

     

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