Mutant p53 depletion by novel inhibitors for hsp40/j-domain proteins derived from the natural compound plumbagin

HIGHLIGHTS

• who: Mohamed Alalem and collaborators from the Department of Pediatrics, Division of Hematology and Oncology, Children's Mercy Research Institute, Kansas City, MO, USA Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA have published the research: Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin, in the Journal: Cancers 2022, 14, 4187. of 14/09/2015
• what: Hereafter, the authors focused on the PLTFBH compound. PLTFBH Selectively Decreases Protein Levels of Certain Members of HSP40/JDPs Although the authors show specificity of . . .
  

   

  

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