Mutant tdp-43 and fus cause age-dependent paralysis and neurodegeneration in c. elegans

HIGHLIGHTS

• who: Alexandra Vaccaro et al. from the The Research Centre of the University of Montreal Hospital Centre, Université de Montréal, Montréal, Québec, Canada, Centre of Excellence in Neuromics, Université de have published the research work: Mutant TDP-43 and FUS Cause Age-Dependent Paralysis and Neurodegeneration in C. elegans, in the Journal: (JOURNAL) of February/21,/2012
• how: To examine if protein misfolding is more pronounced for strains expressing mTDP-43 and mFUS the authors used a biochemical assay to detect protein aggregation. The authors hypothesized that placing worms in liquid culture . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.